ea0081p543 | Adrenal and Cardiovascular Endocrinology | ECE2022
Armignacco Roberta
, Daniel De Murat
, Jouinot Anne
, Bouys Lucas
, Perlemoine Karine
, Letourneur Franck
, Adoux Lucie
, Zennaro Maria-Christina
, Bertherat Jerome
, Assie Guillaume
Background: Cushings syndrome, caused by an excess of circulating glucocorticoids, is associated with high morbidity and presents high inter-individual variability. The earlier the diagnosis, the better the treatment effectiveness and the prognosis. Hormone assays, routinely used, contribute to identify Cushings syndrome. However, no biomarker is currently available to directly quantify the biological action of glucocorticoids. Blood samples represent an easily obt...